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KMID : 0882419930450030396
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Korean Journal of Medicine
1993 Volume.45 No. 3 p.396 ~ p.399
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Two Cases of Acute Renal Failure in Paroxysmal Nocturnal Hemoglobinuria
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양태영
조희충/최연수/김용화/조영호/정춘혜/홍순표
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Abstract
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aroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder involving multiple hematopoietic cell lines characterized by hemolytic anemia with accompanying hemoglobinuria
usually occuring at night. Exacerbation of the hemolytic process following the transfusion of
whole blood or plasma, such as occurs in paroxysmal nocturnal hemoglobinuria has been
reported to precipitate acute renal failure.
We present here two cases of paroxysmal nocturnal hemoglobinuria developed acute renal
failure (ARF) due to hemolytic transfusion reaction and treated by steroid, diuretics and fluid
therapy.The first case was refered to the hospital that had been following up before and the
second was discharged with symptomatic and hematologic improvement.
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KEYWORD
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